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IgG responses to RAP1 are short-lived after recovery from P. falciparum infection. Reactivities of rRAP1 antigens with IgG in sera donated by five different individuals on the indicated dates before, during, and after drug-cured clinical malarial episodes (asterisks) are shown. Note a rapid decline of antibody levels in all cases. A cutoff value indicated by a horizontal line is that of P4; cutoffs for the other antigens were lower (see Materials and Methods).
