Table 1.
Demographics and clinical variables
Variable | No Dementia n = 72 | Dementia n = 89 | p |
Demographics | |||
Age at death, y | 98 (96,100) | 98 (96,99) | 0.81 |
Females, % | 57/72 (79%) | 77/89 (86%) | 0.30 |
Race, % | 0.58 | ||
Non-Hispanic white decedent | 71/72 (99%) | 88/89 (99%) | |
Non-Hispanic black decedent | 1/72 (1%) | 1/89 (1%) | |
Education, years | 15 (12,16) | 14 (12,16) | 0.08 |
APOE ɛ2 presence, % | 20/72 (28%) | 11/88 (12%) | 0.03 |
APOE ɛ4 presence, % | 16/72 (22%) | 24/88 (27%) | 0.58 |
Last MMSE | 27 (24,28) | 17 (11,24) | <0.001 |
Vascular risk factors or comorbidities | |||
Cerebrovascular Disease, % | 22/72 (31%) | 37/89 (42%) | 0.20 |
Coronary Artery Disease, % | 31/72 (43%) | 23/89 (26%) | 0.03 |
Hypertension, % | 59/72 (82%) | 63/89 (71%) | 0.15 |
Heart Failure, % | 30/72 (42%) | 29/89 (33%) | 0.31 |
Peripheral Vascular Disease, % | 15/72 (21%) | 17/89 (19%) | 0.94 |
Diabetes Mellitus, % | 2/72 (3%) | 10/89 (11%) | 0.08 |
Smoking status | 0.07 | ||
Never-smoker, % | 43/64 (67%) | 59/72 (82%) | |
Former smoker, % | 10/64 (16%) | 9/72 (12%) | |
Current smoker, % | 11/64 (17%) | 4/72 (6%) | |
Cancer, % | 41/72 (57%) | 27/89 (30%) | 0.001 |
Data are presented as median (25th percentile, 75th percentile) or as a proportion. APOE, Apolipoprotein E; MMSE, Mini-Mental State Examination.