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. 2022 Feb 4;128(11):2241–2248. doi: 10.1017/S0007114521005195

Table 3.

Adjusted odds ratio (95 % confidence intervals) in relation to the odds of a low cognitive score by mushroom intake, NHANES 2011–2014 (Odds ratios and 95 % confidence intervals)

Mushroom intake
Middle Highest
Lowest Odds ratio 95 % confidence intervals Odds ratio 95 % confidence intervals P-trend
Intake, g/4184 KJ (1000 kcal)/d
  Median 0 2·4 13·4
  Range 5·1 92·4
DSST < 34
No. of cases 661 9 5
Model 1 1 (reference) 0·91 0·24, 3·41 0·21 0·07, 0·61 0·01
Model 2 1 (reference) 1·33 0·28, 6·23 0·29 0·11, 0·76 0·06
CERAD-WL < 17
No. of cases 819 10 12
Model 1 1 (reference) 0·63 0·21, 1·92 0·40 0·20, 0·84 0·01
Model 2 1 (reference) 0·69 0·24, 2·02 0·43 0·18, 0·99 0·04
CERAD-DR < 5
No. of cases 705 10 15
Model 1 1 (reference) 0·34 0·13, 0·91 1·25 0·52, 2·98 0·82
Model 2 1 (reference) 0·36 0·14, 0·95 1·41 0·58, 3·38 0·61
AF < 14
No. of cases 831 12 13
Model 1 1 (reference) 0·90 0·29, 2·77 0·73 0·28, 1·90 0·89
Model 2 1 (reference) 1·17 0·33, 4·12 0·74 0·30, 1·84 0·56

AF, Animal Fluency Test; CERAD-DR, Consortium to Establish a Registry for Alzheimer’s Disease Delayed Recall test; CERAD-WL, Consortium to Establish a Registry for Alzheimer’s Disease Word Learning test; DSST, Digit Symbol Substitution Test.

Model 1: Age, sex, education adjusted.

Model 2: Model 1 + further adjustment of ethnicity-race, ratio of family income to poverty level, smoking status, physical activity, history of diabetes, history of CVD, total energy, alcohol intake, HEI-2015 score.