TABLE 1.

Comparison of disease progression in IL-5^−/− and WT mice^a

Stage of disease (wk)	Mice	Worm burden	Hepatic egg burden/g	Granuloma vol (mm3)	Cellular infiltrate in granuloma
					% Eosinophils	% Mast cells
Acute (8)	IL-5−/−	22.7 ± 2.2	12,141 ± 2,866	28.9 ± 3.0	7.5 ± 1.8b	NDc
	WT	20.0 ± 6.4	15,840 ± 2,344	26 ± 4.8	55 ± 2.4	ND
Chronic (>16)	IL-5−/−	11.7 ± 2.2	8,500 ± 884	15.1 ± 1.3	0.7 ± 0.2b	8.8 ± 0.8b
	WT	12.0 ± 0.5	6,400 ± 1,415	18.6 ± 4.7	38.3 ± 5.9	2.3 ± 0.2

^aResults are means ± standard errors and are representative of at least three separate experiments. 

^bP < 0.05 compared with WT mice. 

^cND, none detected.