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. 2022 Oct 18;65(21):14792–14808. doi: 10.1021/acs.jmedchem.2c01311

Table 2. Antiviral Evaluation of Series 1 against EV-D68a in RD Cellsb.

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a

EV-D68 strain: STL-2014-12.

b

EC50: concentration that effectively inhibited the cytopathic effect by 50% in Rhabdomyosarcoma cell lines (RD cells).

c

CC50: concentration that inhibited the normal uninfected cell viability by 50%, or the maximum soluble concentration which started from 200 μM in serial 3-fold dilutions.

d

Selectivity index (SI) calculated as CC50/EC50 ratio.

e

NA: no activity.