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. 2022 Oct 21;65(21):14655–14672. doi: 10.1021/acs.jmedchem.2c01175

Table 5. Intracellular pH (pHi) Values of Sensitive, Wild-Type Resistant, and P-gp KO- and hCA XII KO-Resistant HT29 and A549 Cells.

cell lines pHia cell lines pHia
HT29 7.41 ± 0.05 A549 7.39 ± 0.03
HT29/DOX 7.64 ± 0.06 A549/DOX 7.66 ± 0.06
HT29/DOX KO P-gp 7.61 ± 0.08 A549/DOX KO P-gp 7.69 ± 0.05
HT29/DOX KO CAXII 7.42 ± 0.07 A549/DOX KO CAXII 7.41 ± 0.03
a

The pHi was measured by a pH-sensitive fluorescent probe. Data are means ± standard deviation (SD) (n = 3).