Skip to main content
. 2021 Nov 19;45(5):798–805. doi: 10.1016/j.bj.2021.11.007

Table 1.

Analysis of risk factors of HB vaccine efficacy and HBV infection rate among high-risk children born to HBeAg-positive mothers.

Factors Comparison HB vaccine responders n = 109 (55.6%) HBsAg carrier n = 21 (10.7%) Subjects recovered from HBV infection n = 65 (33.2%) Subjects infected with HBV n = 86 (43.9) ap bp cp
Sex Male 51 (46.8) 10 (47.6) 28 (43.1) 38 (44.2) 0.944 0.716 0.717
Female 58 (53.2) 11 (52.4) 37 (56.9) 48 (55.8)
Time interval from birth to HBIG ≤3 h 70 (76.1) 14 (73.7) 39 (70.9) 53 (71.6) 0.777 0.817 0.514
>3 h 22 (23.9) 5 (26.3) 16 (29.1) 21 (28.4)
Gestational age at birth ≥37 weeks 84 (87.5) 19 (100) 50 (83.3) 69 (87.3) 0.212 0.107 0.975
<37 weeks 12 (12.5) 0 (0) 10 (16.7) 10 (12.7)
Mode of delivery CS 20 (20.8) 1 (5.3) 23 (37.7) 24 (30.0) 0.190 0.007∗ 0.162
NSD 76 (79.2) 18 (94.7) 38 (62.3) 56 (70.0)
Maternal gestational diabetes No 95 (99.0) 19 (100) 57 (95.0) 76 (96.2) 1.000 1.000 0.329
Yes 1 (1.0) 0 (0) 3 (5.0) 3 (3.8)
Baby's birth body weight ≥2500 g 86 (89.6) 16 (84.2) 53 (88.3) 69 (87.3) 0.448 0.696 0.643
<2500 g 10 (10.4) 3 (15.8) 7 (11.7) 10 (12.7)
Baby's birth body height ≥45 cm 89 (92.7) 17 (89.5) 52 (86.7) 69 (87.3) 0.642 1.000 0.233
<45 cm 7 (7.3) 2 (10.5) 8 (13.3) 10 (12.7)
Second stage of labor ≥1 h 27 (35.5) 7 (38.9) 11 (28.9) 18 (32.1) 0.789 0.457 0.685
<1 h 49 (64.5) 11 (61.1) 27 (71.1) 38 (67.9)
Apgar score at 10 min ≥9 92 (95.8) 19 (100) 56 (93.3) 75 (94.9) 1.000 0.567 1.000
<9 4 (4.2) 0 () (6.7) 4 (5.1)

p < 0.01.

a

HB vaccination responders versus HBsAg carriers.

b

HBsAg carriers versus subjects who had recovered from HBV infection.

c

HB vaccination responders versus subjects infected with HBV.