Table 2.
Risk factors for thrombocytopenic event <100 × 109/L using multiple Cox proportional hazards models.a
| HCV (n = 1436) | HBV (n = 1432) | |||||
|---|---|---|---|---|---|---|
| Platelet events | 59 | 26 | ||||
| Follow-up (year) | 2670.72 | 8173.59 | ||||
| Incidence (per 100,000 person-years) |
2209.14 |
318.10 |
||||
| Characteristic | AHR | 95% CI | p | AHR | 95% CI | p |
| Initial platelet level | ||||||
| 1 (≥150 × 109/L) | 1.00 | 1.00 | ||||
| 2 (≥100–149 × 109/L) | 7.90 | 3.80–16.43 | <0.001 | 8.75 | 3.50–21.86 | <0.001 |
| Total bilirubin —mg/dL | ||||||
| ≥2.0 | 5.83 | 2.35–14.46 | <0.001 | |||
| <2.0 | 1.00 | |||||
| Spleen index | ||||||
| ≥20 | 2.92 | 1.53–5.56 | <0.001 | |||
| <20 | 1.00 | |||||
| Cirrhosis | ||||||
| Positive | 3.27 | 1.60–6.67 | <0.001 | |||
| Negative | 1.00 | |||||
Abbreviations: HCV: hepatitis C virus; HBV: hepatitis B virus; AHR: adjusted hazard ratio; CI: confidence interval.
a
Only the covariates with statistical significance in the multiple Cox model were presented.