Table 2.

Summary of circRNA acting on malignant biological behaviors of lung cancer through ceRNA mechanism.

circRNA	Dysregulation	Cell lines	Function	Sponge target	Ref.
circ_11780	Down	A549, H226	Proliferation (−), migration (−), invasion (−)	miR-544a	[34]
circGFRA1	Up	A549, H838	Proliferation (+)	miR-188–3p	[36]
circ_0012673	Up	A549, H23	Proliferation (+), apoptosis (−), migration (+), EMT (+)	miR-320a	[38]
circ-0000211	Up	A549, H1299, H1650	Migration (+), invasion (+)	miR-622	[39]
circ-ABCB10	Up	A549, H292	Proliferation (+), migration (+)	miR-556–3p	[40]
circ_0000326	Up	A549, H1299	Proliferation (+), apoptosis (−), migration (+)	miR-338–3p	[41]
circ_0014130	Up	PC-9, A549	Proliferation (+), apoptosis (−), invasion (+)	miR-136–5p	[42]
circ-SOX4	Up	A549, SPC-A1	Proliferation (+), migration (+), invasion (+)	miR-1270	[43]
circCCDC66	Up	A549, H1299	Proliferation (+), apoptosis (−), migration (+), invasion (+)	miR-33a-5p	[44]
circCDR1as	Up	A549, Calu-3	Proliferation (+), apoptosis (−), migration (+), invasion (+)	miR-219a-5p	[45]
circ_0058124	Up	A549, H1975	Proliferation (+), apoptosis (−), migration (+), invasion (+)	miR-1297	[46]
circ-MTO1	Down	A549, SPC-A1	Proliferation (−)	miR-17	[47]
cMras	Down	A549, H1299	Proliferation (−), migration (−)	miR-567	[48]
circ-IGF1R	Down	PC9, A549	Migration (−), invasion (−)	miR-1270	[49]
circCRIM1	Down	A549, H1299, SPC-A1	Migration (−), invasion (−)	miR-93, miR-182	[50]
circ_0007059	Down	A549, H1975	Proliferation (−), EMT (−)	miR-378	[51]
circ_0006427	Down	SPC-A1, Calu-3	Proliferation (−), migration (−), invasion (−)	miR-6783–3p	[52]
circPTPRA	Down	H23, H1755, H522	Migration (−), invasion (−), EMT (−)	miR-96–5p	[53]
circSMARCA5	Down	A549	Proliferation (−), migration (−), invasion (−)	miR-19b-3p	[54]
circ_0002483	Down	A549, H1299	Proliferation (−), migration (−), invasion (−)	miR-182–5p	[55]
circ_0078767	Down	A549, H23	Proliferation (−), apoptosis (+), invasion (−)	miR-330–3p	[56]