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Effect of CSE on the radiographic findings.
| Groups | Joint space radiodensity | Osteophytic reactivity | Bone changes |
|---|---|---|---|
| Sham | Normal (-) | Normal (-) | Normal (-) |
| Osteoarthritis control | Extreme (++++) | Extreme (++++) | Extreme (++++) |
| Ibuprofen 40 mg/kg | Moderate (++) | Low (+) | Moderate (++) |
| CSE 100 mg/kg | High (+++) | Moderate (++) | Moderate (++) |
| CSE 200 mg/kg | Very low (+/-) | Low (+) | Low (+) |
| CSE 300 mg/kg | Very low (+/-) | Very low (+/-) | Very low (+/-) |
CSE, Crataegus sinaica methanolic extract.
