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Swiss NIH mice infected with wild-type C. rodentium showed severe colonic hyperplasia compared to mice infected with an intimin mutant strain. Crypt lengths were measured on days 2, 6, and 12 postinfection. Mean crypt lengths in the colons of mice infected with wild-type C. rodentium (open bars) were significantly greater than those of mice infected with the control mutant strain (closed bars). Error bars represent standard errors. Each group contained five mice. ∗, P < 0.05).
