. 2022 Oct 18;13(11):1763–1768. doi: 10.1021/acsmedchemlett.2c00378

Table 2. Potency of Analogues Modified at the C11 and C13 Positions against hNa_V1.7 and Off-Target hNa_V Isoforms.

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IC₅₀ values determined by manual patch clamp electrophysiology; data represent the mean of at least two assay determinations.

Data obtained from a single assay.

NT = not tested.

IC₅₀ value reported in ref (15).

Table 2. Potency of Analogues Modified at the C11 and C13 Positions against hNaV1.7 and Off-Target hNaV Isoforms.