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. 2022 Oct 6;13(11):1730–1738. doi: 10.1021/acsmedchemlett.2c00334

Table 3. Mouse PK Profile of Compound 30.

admin. dose (mg/kg) Tmax (h) C0 (ng h) Cmax (ng h) AUC(0–t) (ng h/mL) AUC(0–∞) (ng h/mL) Cl (L h–1 kg–1) t1/2 (h) MRT (0–t) (h) F (%)
iga 20 0.25 4075 13379 13476 1.18 2.65 253.29
ivb 1 1075 264 264 3.78 0.20 0.26
a

Intragastric administration (oral gavage).

b

Intravenous injection.