Fig. 7.

Relative abundance (RA) of terminal glycan structures on gastric mucins from Helicobacter spp.-infected and -noninfected humans. The datasets contain the RAs of the structures in all four mucin sources from each individual and have been grouped into Leb-positive (Leb Pos) and Leb-negative (Leb Neg) individuals either negative (Non-inf) or positive (Inf) for Helicobacter spp. A, the data points represent the Leb content of the mucins based on ELISA. B, J99 wt binding correlation with the amplitude of Leb in all four fractions from Leb-positive mucins. White circles denote mucins that did not bind statistically significantly better to J99 wt than wells with no mucins, and black circles denote mucins that bound to J99 wt. C–I, the data points represent the RA of glycan structures as determined by mass spectrometry (MS). In G and I, secretors are denoted with circles and nonsecretors as squares. Statistics. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, two-way ANOVA, the bars represent the mean. Leb, Lewis b.