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Dextran brain and CSF concentration ratios. A Cortex/plasma, B Brainstem/plasma and C CSF/plasma concentration ratios (%) in E16, E19, P4 and adult rats. Samples collected 5 min following i.v. injection of 70 kDa 3H-dextran. Note no difference in brain ratios between the ages (A & B). Each point represents result from a single animal. Mean ± SD; n = 3–6. *p < 0.05, **p < 0.01
