Table 4.
CMR characteristics and longitudinal changes by ventricular dominance
| Variable | Dominant ventricle | p-value | |
|---|---|---|---|
| LV (n = 83) | RV (n = 73) | ||
| Follow up time since first CMR, years Median (IQR) | 10.7 (6.4, 14.5) | 9.2 (5.8, 14.3) | 0.13 |
| Composite outcome | 0.03 | ||
| Listing/Death/Transplant | 7 (8.4%) | 15 (20.5%) | |
| Free of event | 76 (91.6%) | 58 (79.5%) | |
| Male | 51 (61.4%) | 49 (67.1%) | 0.461 |
| At the first CMR | |||
| Age at CMR, years | 19.7 ± 10.0 | 15.6 ± 8.7 | 0.008 |
| Height, cm | 155 ± 20 | 149 ± 24 | 0.10 |
| Weight, kg | 54.5 ± 19.9 | 50.0 ± 23.1 | 0.19 |
| BSA, m2 | 1.52 ± 0.37 | 1.42 ± 0.44 | 0.14 |
| EDVI, ml/BSA1.3 | 88.9 ± 28.6 | 109.0 ± 43.3 | < 0.001 |
| ESVI, ml/BSA1.3 | 42.3 ± 20.4 | 53.8 ± 31.7 | 0.009 |
| Massi, g/BSA1.3 | 63.3 ± 23.9 | 60.5 ± 22.3 | 0.46 |
| EF, % | 53.9 ± 10.3 | 52.7 ± 9.6 | 0.42 |
| Mass-to-volume ratio | 0.76 ± 0.31 | 0.62 ± 0.30 | 0.005 |
| ESWS, kPa | 16.0 ± 5.3 | 19.7 ± 7.7 | 0.006 |
| At the last CMR | n = 83b | n = 72 | |
| Age at CMR, years | 25.7 ± 11.0 | 21.5 ± 9.8 | 0.013 |
| Time between 2 CMRs, years | 6.0 ± 4.1 | 5.7 ± 4.0 | 0.68 |
| Median (IQR) | 5.5 (2.0, 8.6) | 4.8 (2.6, 8.7) | 0.62 |
| BSA, m2 | 1.70 ± 0.34 | 1.67 ± 0.41 | 0.59 |
| EDVI, ml/BSA1.3 | 96.7 ± 25.4 | 117.4 ± 49.1 | 0.002 |
| ESVI, ml/BSA1.3 | 46.4 ± 18.7 | 64.4 ± 44.8 | 0.002 |
| Mass index, g/BSA1.3 | 54.5 ± 16.3 | 53.9 ± 20.0 | 0.86 |
| EF, % | 53.2 ± 8.3 | 48.3 ± 11.0 | 0.002 |
| Mass-to-volume ratio | 0.58 ± 0.15 | 0.49 ± 0.16 | < 0.001 |
| ESWS, kPa | 16.6 ± 7.1 | 21.4 ± 8.0 | < 0.001 |
| Annual Change in CMR (last-first)/(years between last and first) | |||
|
EDVI, ml/BSA1.3/year Median (IQR) |
1.09 (− 0.69, 3.45)a | 0.71 (− 1.61, 2.75) | 0.48 |
|
ESVI, ml/BSA1.3/year Median (IQR) |
0.69 (− 0.70, 1.99)a | 1.22 (− 0.74, 2.66)a | 0.24 |
|
Mass index, g/BSA1.3/year Median (IQR) |
− 1.18 (− 2.98, 0.55)a | − 0.93 (− 3.47, 1.05)a | 0.70 |
|
EF, %/year Median (IQR) |
− 0.12 (− 0.98, 0.66) | − 0.62 (− 2.21, 0.27)a | 0.02 |
|
Mass-to-volume ratio, /year Median (IQR) |
− 0.02 (− 0.05, 0.01)a | − 0.01 (− 0.03, 0.01)a | 0.24 |
|
ESWS, kPa/year Median (IQR) |
0.31 (− 0.37, 0.78) | 0.30 (− 0.78, 1.40) | 0.81 |
Bold indicates p-value < 0.05
aIndicates that the change is significantly different from 0
bOne patient had transplant listing prior to their last CMR