Table 2.
PGAM5 levels in subgroups of hypertension (HTN), diabetes mellitus (DM), and age.
| PGAM5 (pg/ml) | PD median (IQR) | Control mean (IQR) | p-value |
|---|---|---|---|
| Non-HTN (nPD = 76, nHC = 24) | 860.48 (790.38, 942.36) | 750.97 (665.49, 812.99) | <0.0001* |
| HTN (nPD = 48, nHC = 26) | 875.11 (795.53, 1044.50) | 788.09 (733.43, 857.71) | 0.0008* |
| Non-DM (nPD = 99, nHC = 48) | 860.55 (793.59, 945.94) | 780.32 (679.37, 831.07) | <0.0001* |
| DM (nPD = 25, nHC = 2) | 899.66 (797.93, 1061.87) | 757.17 (707.95, 806.38) | 0.114 |
| Age ≤50 (nPD = 7, nHC = 1) | 932.52 (858.47, 1045.67) | 690.16 | NR |
| 50 <age ≤ 60 (nPD = 25, nHC = 12) | 839.76 (792.42, 983.55) | 823.02 (679.41, 892.18) | 0.1166 |
| 60 < age ≤ 70 (nPD = 56, nHC = 26) | 871.77 (789.38, 961.85) | 760.87 (672.88, 807.61) | <0.0001* |
| Age >70 (nPD = 36, nHC = 11) | 849.23 (785.25, 953.77) | 786.80 (756.30, 813.55) | 0.0407* |
Data are expressed as mean, median, or n (%). IQR, interquartile range; HTN, hypertension; DM, diabetes mellitus; non-HTN, non-hypertension; non-DM, non-diabetes mellitus.Asterisk (*) indicates statistical significance (P < 0.05).