Table 3.

Indicators associated with 1-month, 3-month, and 6-month mortality in multivariate analyses in patients with decompensated liver cirrhosis in cohort I& II.

	Cohort I						Cohort II (validation cohort)
Variables	1 month OR (95% CI)	p	3 months OR (95% CI)	p	6 months OR (95% CI)	p	1 month OR (95% CI)	p	3 months OR (95% CI)	p	6 months OR (95% CI)	p
PLT (109/L)	1.008 (1.003–1.014)	0.004	1.006 (1.001–1.012)	0.013	1.005 (1.000–1.010)	0.026	1.009 (0.995–1.023)	0.197	1.006 (0.995–1.018)	0.285	1.003 (0.992–1.014)	0.595
ALB (g/L)	0.959 (0.844–1.082)	0.504	0.943 (0.850–1.040)	0.251	0.913 (0.836–0.992)	0.037	0.851 (0.688–1.053)	0.137	0.901 (0.774–1.049)	0.179	0.877 (0.776–0.991)	0.036
TBIL (umol/L)	0.997 (0.977–1.015)	0.766					0.998 (0.972–1.024)	0.866
AST (U/L)	1.001 (0.997–1.006)	0.531	1.002 (0.998–1.006)	0.395			0.943 (0.888–1.001)	0.054	0.988 (0.972–1.005)	0.165
PT (s)	1.161 (0.900–1.507)	0.251	0.999 (0.795–1.249)	0.996	1.032 (0.853–1.249)	0.743	0.970 (0.782–1.203)	0.782	0.942 (0.771–1.150)	0.554	1.148 (0.924–1.425)	0.213
MELD score	1.087 (0.887–1.307)	0.395	1.125 (0.970–1.300)	0.114	1.070 (0.942–1.212)	0.284	1.297 (1.002–1.680)	0.049	1.238 (1.032–1.487)	0.022	1.05 (0.918–1.214)	0.445
LWR		0.002		0.002		0.014		0.095		0.007		0.026
Low	Ref		Ref		Ref		Ref		Ref		Ref
High	0.139 (0.037–0.456)		0.211 (0.075-0.574)		0.234 (0.064–0.679)		0.245 (0.047–1.276)		0.169 (0.047–0.613)		0.271 (0.085–0.858)

PLT: platelet; ALB: albumin; TBIL: total bilirubin; AST: aspartate aminotransferase; PT: prothrombin time; MELD: Model for End-stage Liver Disease; LWR: lymphocyte-to-white blood cell ratio; OR: odds ratio; CI: confidence interval.

Age, sex, haemoglobin, PLT, ALB, TBIL, AST, PT, LWR, MELD score, alanine aminotransferase, γ-glutamyl transpeptidase and creatinine were included in the univariate logistic regression analysis. Variables that did not have a significant effect on mortality in the univariate logistic regression analysis were not included in the multivariate logistic regression analysis.