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. 2022 Nov 14;22:274. doi: 10.1186/s12866-022-02686-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Differences in alpha diversity between RP/post-RP and non-COV. (a) Forest plot of the differences in Shannon’s diversity index between RP/post-RP and non-COV. (b) Forest plot of the differences in observed species between RP/post-RP and non-COV. (c) Boxplots showing standardized Shannon’s diversity index by SARS-CoV-2 infection status (red = COV, purple = RP, blue = post-RP, and green = non-COV). COV, samples derived from COVID-19 patients; RP, samples derived from COVID-19 recovered patients who with clearance of SARS-CoV-2 RNA (negative conversion of viral RNA) within one month; those with negative conversion of viral RNA more than three months were especially grouped as post-RP; non-COV, samples derived from non-COVID-19 individuals