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. 2022 Nov 9;50(6):146. doi: 10.3892/ijmm.2022.5202

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Increased autophagy in Mst1-deficient endothelial cells. (A) TEM images of CMECs. Scale bar, 2 µm. (B) Representative immunofluorescence images of p62 and LC3B in mouse myocardium; magnification, ×200. (C) Quantitative assessment of immunofluorescence images; n=3. (D) Representative immunofluorescence images of p62 and LC3B in CMECs; magnification, ×200. (E) Quantitative assessment of immunofluorescence images; n=3. ^*P<0.05. WT, wild-type; Mst1, mammalian ste20-like kinase 1; HP, hypertensive/hypertension; LC3B, microtubule-associated proteins 1A/1B light chain 3B; CMECs, cardiac microvascular endothelial cells; KD, knockdown; NC, negative control.