Figure 7.

Modulation of core autophagy protein expression by Mst1. (A) Representative western blots of Mst1, p-Mst1, Beclin-1, p62, LC3B and β-actin proteins in CMECs and the quantitative assessment of the western blots; n=4. (B) Representative western blots of Mst1, p-Mst1, Beclin-1, p62, LC3B and β-actin proteins in mouse myocardium and the quantitative assessment of the western blots; n=3. ^*P<0.05, ^**P<0.01, ^***P<0.001 and ^****P<0.0001. Mst1, mammalian ste20-like kinase 1; LC3B, microtubule-associated proteins 1A/1B light chain 3B; CMECs, cardiac microvascular endothelial cells; WT, wild-type; HP, hypertensive/hypertension; KD, knockdown; NC, negative control.