Table 1.
Demographics.
| CRC (12) | AA (10) | Polyps (11) | Control (20) | |
|---|---|---|---|---|
| Age (median [IQR]) | 67 [60–71] | 71 [70–73] | 73 [60–75] | 67 [62–75] |
| Gender (male No [%]) | 6 [50] | 9 [90.0] | 9 [81.2] | 14 [70] |
| BMI (median [IQR]) | 25.1 [23.7–31.1] | 26.9 [23.5–28.4] | 26.8 [23.7–29.1] | 25.5 [22.9 − 28.7] |
| Smoking status (No[%]) | ||||
| Never smoked | 2 [16.7] | 1 [10] | 3 [27.3] | 6 [13] |
| Stopped smoking | 9 [75.0] | 8 [80] | 6 [44.6] | 12 [60] |
| Actively smoking | 1 [8.33] | 1 [10] | 2 [18.2] | 2 [10] |
| Endoscopy indication (No [%]) | ||||
| Positive FIT | 6 [50] | 3 [13] | 3 [27.3] | 3 [14] |
| Rectal blood loss | 4 [33.3] | 4 [15] | 0 [0] | 1 [5.0] |
| Abdominal pain | 1 [8.33] | 1 [10] | 1 [9.1] | 6 [13] |
| Diarrhea | 0 [0] | 0 [0] | 1 [9.1] | 0 [0] |
| Change in bowel habits | 1 [8.33] | 1 [10] | 1 [9.1] | 3 [14] |
| Polyp surveillance | 0 [0] | 1 [10] | 2 [18.2] | 2 [10] |
| Surveillance on family history | 0 [0] | 1 [10] | 0 [0] | 1 [5.0] |
| Incontinence | 0 [0] | 0 [0] | 1 [9.1] | 0 [0] |
| Coincidental radiologic finding | 0 [0] | 0 [0] | 0 [0] | 0 [0] |
| Surveillance after CRC | 0 [0] | 0 [0] | 2 [18.2] | 1 [5.0] |
| Anemia | 1 [8.33] | 0 [0] | 0 [0] | 1 [5.0] |
| Localization largest abnormality (No [%])* | ||||
| Cecum | 0 [0] | 1 [10] | 2 [18.2] | NA |
| Ascending colon | 1 [8.33] | 1 [10] | 3 [27.3] | NA |
| Flexura Hepatica | 1 [8.33] | 0 [0] | 0 [0] | NA |
| Transversal colon | 0 [0] | 0 [0] | 1 [9.1] | NA |
| Flexura lienalis | 0 [0] | 1 [10] | 0 [0] | NA |
| Descending colon | 0 [0] | 0 [0] | 0 [0] | NA |
| Sigmoid | 6 [50] | 4 [15] | 4 [36.4] | NA |
| Rectosigmoid | 2 [16.7] | 0 [0] | 0 [0] | NA |
| Rectum | 1 [8.33] | 2 [16] | 1 [9.1] | NA |
| AA Characteristics (No [%]) | ||||
| High grade dysplasia | NA | 0 [0] | NA | NA |
| Villous histology | NA | 4 [15] | NA | NA |
| >1 cm | NA | 9 [90] | NA | NA |
| Polyp characteristics (No [%]) | ||||
| No dysplasia | NA | NA | 0 [0] | NA |
| Hyperplastic | NA | NA | 0 [0] | NA |
| Low grade dysplasia | NA | NA | 11 [100] | NA |
| Number of adenomas removed (median [IQR]) | 2 [1–4] | 3 [2–4] | 2 [1–3] | NA |
Demographics of study participants. Abbreviations: CRC = colorectal cancer, AA = advanced adenoma, IQR = interquartile range, NA = not applicable. In this study, AA and polyps were combined into one adenoma group. All CRC were adenocarcinomas *Information on localization of lesion missing for one participants of the CRC and AA group.