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. Author manuscript; available in PMC: 2022 Nov 14.

Published in final edited form as: J Hepatol. 2020 Dec 1;74(5):1145–1154. doi: 10.1016/j.jhep.2020.11.037

Table 1.

Multivariate analysis for clinical parameters in iCCA cohort.

	Univariate analysis		Multivariate analysis
	Hazard ratio^*	p value^**	Hazard ratio^*	p value^**
Age	0.98997 (0.9557–1.025)	0.575	0.9794 (0.9421–1.018)	0.2917
Sex
Female	1.265e⁺⁰⁷ (0–Inf)	0.996	1.4802 (0.7140–3.069)	0.2917
Male	8.148e⁺⁰⁶ (0–Inf)	0.996	n.a.	n.a.
Albumin	0.8299 (0.4837–1.424)	0.499	0.5502 (0.2826–1.071)	0.0788
ALT	0.995309 (0.9885–1.002)	0.18	0.992 (0.9832–1.001)	0.076
Bilirubin	0.98898 (0.9228–1.06)	0.754	1.0072 (0.9430–1.076)	0.8311
INR	0.7651 (0.3556–1.646)	0.494	0.7979 (0.3207–1.985)	0.6273
CD40 low vs. high	2.7052 (1.811–6.1961)	0.0186^*	3.0275 (1.2377–7.405)	0.0152^*

^*

Hazard ratios were determined using Cox proportional regression.

^**

p value was determined using the log-rank test.

ALT, alanine aminotransferase; INR, international normalized ratio.