eAPPENDIX.
Variable Definitions
| Cohort definition | ICD-9 diagnosis codes/beginnings |
|---|---|
| MGUS | 273.1 |
|
| |
| Multiple myeloma | 203.00, 203.01, 203.02 |
|
| |
| Mental and behavioral disorders | |
| Alcohol use disorder | 303, 305.0 |
| Substance use disorder | 304, 305.2–305.9 |
| Nicotine dependence | 305.1, V15.82 |
| Major depressive disorder | 311, 296.2, 296.3 |
| Posttraumatic stress disorder | 309.81 |
| Schizophrenia or bipolar disorder | 295, 296.0, 296.1, 296.4–296.8 |
| Anxiety | 300.00–300.02 |
| Overweight or obesity | 278.00, 278.01, 278.02 |
|
| |
| Other common conditions | |
| Dyslipidemia | 272 |
| Hypertension | 401–405 |
|
| |
| Charlson Comorbidity Index conditions | |
| Myocardial infarction | 410, 412 |
| Heart failure | 398.91, 402.01, 402.11, 402.91, 404.01, 404.03, 404.11, 404.13, 404.91, 404.93, 425.4–425.5, 425.7–425.9, 428 |
| Peripheral vascular disease | 093.0, 437.3, 440, 441, 443.1, 443.2, 443.8, 443.9, 447.1, 557.1, 557.9, V43.4 |
| Cerebral vascular | 362.34, 430–438 |
| Dementia | 290, 294.1, 331.2 |
| COPD | 416.8, 416.9, 490–496, 500–505, 506.4, 508.1, 508.8 |
| Rheumatic disease | 446.5, 710.0, 710.1–710.4, 714.0–714.2, 714.8, 725 |
| Peptic ulcer disease | 531–534 |
| Cirrhosis of the liver | 070.22, 070.23, 070.32, 070.33, 070.44, 070.54, 070.6, 070.9, 570, 571, 573.3, 573.4, 573.8, 573.9, V42.7 |
| Diabetes mellitus without complications | 250.0–250.3, 250.8–250.9 |
| Diabetes mellitus with complications | 250.4–250.7 |
| Hemiplegia, paraplegia | 334.1, 342, 343, 344.0–344.6, 344.9 |
| Renal disease | 403.01, 403.11, 403.91, 404.02, 404.03, 404.12, 404.13, 404.92, 404.93, 582, 583.0, 583.1, 583.2, 583.4, 583.6, 583.7, 585, 586, 588.0, V42.0, V45.1, V56 |
| Other cancers | 140–172, 174–195, 200–208, 238.6 |
| Liver failure | 456.0–456.2, 572.2–572.4, 572.8 |
| Metastatic solid tumors (omitted from index) | 196–199 |
| HIV/AIDS | 042, 043, 044 |
|
| |
| Procedures (treatment) | |
| HCT: ICD-9 procedure codes | 41.0, 41.00, 41.04, 41.07, 41.09 |
| HCT: ICD-10 procedure codes | 30230Y0, 30233Y0, 30240Y0, 30243Y0, 30230C0, 30233C0, 30240C0, 30243C0 |
| HCT: CPT code | 38241 |
Abbreviations: HCT, hematopoietic cell transplantation; ICD, International Classification of Diseases; MGUS, monoclonal gammopathy of undetermined significance.