Skip to main content
. Author manuscript; available in PMC: 2022 Nov 18.
Published in final edited form as: Bioconjug Chem. 2022 Jan 18;33(11):1957–1972. doi: 10.1021/acs.bioconjchem.1c00479

Figure 1.

Figure 1.

NP manufacture and properties. Schematics showing the nanoprecipitation method used for NP preparation (A), the composition of the PG, PGM and PGI NPs (B), and the structures of PAMAM and PEI (C). The average hydrodynamic diameter and ζ-potential of the coumarin-6-loaded NPs (D) and SEM images of the PG, PGM and PGI NPs (E). The TEER values of the hCMEC/D3 monocultures representing monolayer of human BBB (F) and the permeability of the coumarin-6-loaded NPs (G)