Comparison 14. Single medication compared with alternate single medication ‐ non‐serious adverse events ‐ musculoskeletal system.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
14.1 Muscle spasm	1	80	Risk Ratio (M‐H, Fixed, 95% CI)	3.00 [0.33, 27.63]
14.1.1 Loxapine (medication 1) versus chlorpromazine (medication 2)	1	80	Risk Ratio (M‐H, Fixed, 95% CI)	3.00 [0.33, 27.63]
14.2 Body weight change	2	93	Mean Difference (IV, Fixed, 95% CI)	‐0.11 [‐0.47, 0.25]
14.2.1 Haloperidol versus phenelzine sulfate	1	64	Mean Difference (IV, Fixed, 95% CI)	‐0.22 [‐0.59, 0.15]
14.2.2 Olanzapine versus fluoxetine	1	29	Mean Difference (IV, Fixed, 95% CI)	2.50 [0.72, 4.28]
14.3 Weight gain (3 or more kg within 4 weeks)	1	51	Risk Ratio (M‐H, Fixed, 95% CI)	4.81 [0.24, 95.58]
14.3.1 Olanzapine versus asenapine	1	51	Risk Ratio (M‐H, Fixed, 95% CI)	4.81 [0.24, 95.58]