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. 2022 Sep 20;146(20):1492–1503. doi: 10.1161/CIRCULATIONAHA.122.060137

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© 2022 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 4. — Assessment of myocardial scar size and transmurality using VNE. Virtual native enhancement (VNE) correlated strongly with late gadolinium enhancement (LGE) in scar size as a volume fraction of the sampled left ventricular (LV) myocardium (A) and in quantifying the mean transmurality of scarred chords per patient (B) in 66 test patients. Mean scar transmurality for each patient was calculated by averaging the transmural scar extent across all the chords (using the centerline chord method) that had at least 1% of scar extent on all available slices. Top, Correlation plots with the linear regression equations, Pearson correlation coefficients (R), statistical significance of correlation (P value), and intraclass correlation coefficients (ICC; 95% CI shown in brackets) provided. Bottom, Bland-Altman plots to analyze any systematic differences between quantification by VNE and LGE.