Table 5.
Colonoscopy quality metrics following a positive mt-sDNA test, following a positive FIT test, or colonoscopy alone (average-risk patientsa).
| Colonoscopy preparation quality | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Colonoscopy after positive mt-sDNA test | Colonoscopy after positive FIT test | Colonoscopy only | Overall P | P value (mt-sDNA vs. FIT) | P value (mt-sDNA vs. colo only) | P value (FIT vs. colo only) | ||||
| Total number of patients | (N = 240) | (N = 194) | (N = 26,221) | |||||||
| Colonoscopy preparation quality | N | % | N | % | N | % | ||||
| Excellent or good | 191 | 91.4 | 170 | 91.4 | 22,347 | 94.5 | 0.0280 | 1.0000 | 0.0648 | 0.0736 |
| Fair | 18 | 8.6 | 16 | 8.6 | 1,296 | 5.5 | ||||
| Missing | 31 | 8 | 2,578 | |||||||
| Withdrawal time and recommended rescreening interval among patients with normal exams with no findings | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Colonoscopy after positive mt-sDNA test | Colonoscopy after positive FIT test | Colonoscopy only | Overall P | P value (mt-sDNA vs. FIT) | P value (mt-sDNA vs. colo only) | P value (FIT vs. colo only) | ||||
| Total number of patients | (N = 55) | (N = 68) | (N = 12,813) | |||||||
| Withdrawal timeb | N | % | N | % | N | % | ||||
| Less than 9 minutes | 20 | 48.8 | 27 | 51.9 | 4,705 | 47.5 | 0.8148 | 0.8358 | 0.8771 | 0.5787 |
| Greater than or equal to 9 minutes | 21 | 51.2 | 25 | 48.1 | 5,191 | 52.5 | ||||
| Missing | 14 | 16 | 2,917 | |||||||
| Recommended colonoscopy rescreening interval | ||||||||||
| N | % | N | % | N | % | 0.0129 | 0.5673 | 0.2419 | 0.0104 | |
| Less than 10 years | 5 | 14.7 | 10 | 21.3 | 910 | 9.3 | ||||
| Greater than or equal to 10 years | 29 | 85.3 | 37 | 78.7 | 8,871 | 90.7 | ||||
| Missing | 21 | 21 | 3,032 | |||||||
Abbreviation: colo, colonoscopy.
aAverage-risk definition: No prior personal history of polyps or colorectal cancer and no first degree family history of colorectal cancer.
bWithdrawal time data is censored at <2 and >10 minutes.