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. 2022 Jun 13;28(16):3546–3556. doi: 10.1158/1078-0432.CCR-22-0368

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©2022 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.

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Figure 1. Molecular landscape of HGSOC. 1Mutation in non-BRCA1/2 HRR genes: 3 BRIP1, 2 CHEK2, 1 RAD51C, 1 PALB2, 1 concurrent BAP1, and NBN. CCNE1 CN gain, ≥4 copies by TaqMan CN assay. EMSY CN amplification, ≥6 copies by TaqMan CN assay. — Molecular landscape of HGSOC. ¹Mutation in non-BRCA1/2 HRR genes: 3 BRIP1, 2 CHEK2, 1 RAD51C, 1 PALB2, 1 concurrent BAP1 and NBN. CCNE1 CN gain, ≥4 copies by TaqMan CN assay. EMSY CN amplification, ≥6 copies by TaqMan CN assay.