Table 2.

Treatment-related adverse events during neoadjuvant therapy.

	Patients (n = 30)
Events	Grade 1–2	Grade 3	Grade 4
Alopecia	30 (100)	0	0
Neurotoxicity	13 (43.3)	0	0
Fatigue	9 (30.0)	0	0
Nausea/vomiting	9 (30.0)	0	0
Hypothyroidism	8 (26.7)	0	0
Leukopenia	7 (23.3)	0	0
Pruritus	6 (20.0)	1 (3.3)	0
Anemia	5 (16.7)	0	0
RCCEP	4 (13.3)	0	0
Myalgia	4 (13.3)	0	0
Arthralgia	3 (10.0)	0	0
Constipation	3 (10.0)	0	0
Diarrhea	2 (6.7)	0	0
Increased aminotransferases	2 (6.7)	0	0
Rash	1 (3.3)	1 (3.3)	0
Increased creatinine	1 (3.3)	0	0
Tuberculosis recurrence	1 (3.3)	0	0
Thrombocytopenia	0	1 (3.3)	0

Abbreviation: RCCEP, reactive cutaneous capillary endothelial proliferation.