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. 2022 May 12;28(16):3433–3442. doi: 10.1158/1078-0432.CCR-22-0305

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©2022 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 3. Outcomes by ESR1 mutation status in ctDNA at day 1 or end of treatment. PFS by treatment (A), OS regardless of treatment (B), and OS by treatment (C). ctDNA = circulating tumor DNA; ESR1 = estrogen receptor 1; FUL = fulvestrant; HR = hazard ratio; mut = mutation; OS = overall survival; PAL = palbociclib; PBO = placebo; PFS = progression-free survival; WT = wild type. — Outcomes by ESR1 mutation status in ctDNA at day 1 or end of treatment. PFS by treatment (A), OS regardless of treatment (B), and OS by treatment (C). ctDNA, circulating tumor DNA; ESR1, estrogen receptor 1; FUL, fulvestrant; HR, hazard ratio; mut, mutation; OS, overall survival; PAL, palbociclib; PBO, placebo; PFS, progression-free survival; WT, wild type.