Figure 3. Transcriptomic analysis of a human model of H3.3-G34R pHGG.
(A) Volcano plot of genes differentially expressed between H3.3-G34R and H3.3-WT human pHGG cells. DNA repair GO genes are highlighted in green, and cell cycle GO genes are highlighted in purple. (B) Selection of differentially enriched GOs between H3.3-G34R and H3.3-WT human pHGG cells, arranged by NES.