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. 2022 Nov 15;132(22):e154229. doi: 10.1172/JCI154229

Figure 4. Transcriptomic analysis of relevant pathways in G34R human pHGG.

Figure 4

(A) Heatmap depicting the gene expression levels of each gene within the “DNA repair” GO, comparing H3.3-G34R with H3.3-WT human pHGG cells. (B) Top most downregulated DNA repair GO genes in H3.3-G34R versus H3.3-WT human pHGG cells. (C and D) Heatmaps highlighting the top most downregulated genes for the GOs “cell cycle” (C) and “chromosome” (D) in H3.3-G34R versus H3.3-WT human pHGG cells.