Table 2.

Differences in biochemical parameters between the study and control group.

Variables	Study group PHPT (N = 48)	Control group (N = 30)	p
Renin (pg/ml)	9.49 (5.1–18.6)	7.82 (4.5–11.3)	NS
Aldosterone (pg/ml)	126.59 ± 58.07	96.37 ± 58.17	0.028
Aldosterone/renin ratio	11.17 (5.97–22.3)	11.48 (7.96–17.12)	NS
PTH (pg/ml)	159.5 (120.9–263)	74 (65–92.70)	≤0.001
Calcium (mmol/l)	2.72 ± 0.39	2.52 ± 0.17	0.010
Ca++ (mmol/l)	1.27 ± 0.19	1.15 ± 0.09	0.003
Phosphorus (mmol/l)	0.82 ± 0.20	0.95 ± 0.18	0.003
25 (OH) D (nmol/l)	48.86 ± 22.54	62.45 ± 23.75	0.040

Normally distributed variables presented as x ± SD and skewed variables by median (interquartile range); NS—not significant; PHPT—Primary hyperparathyroidism; Ca⁺⁺—ionized calcium.