TABLE 1.
Cell type | % of positive cellsb after following treatment:
|
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---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen and no infection
|
Estrogen and infection
|
Infection and no estrogen
|
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1 | 2 | 3 | 5 | 1 | 2 | 3 | 5 | 1 | 2 | 3 | 5 | |
αβ TCR+ CD4+ | 40 | 29 | 32 | 35 | 42 | 28 | 30 | 32 | 39 | 30 | 23 | 29 |
γδ TCR+ CD4+ | 20 | 19 | 20 | 21 | 22 | 16 | 21 | 19 | 23 | 20 | 19 | 17 |
γδ TCR+ CD4− | 12 | 3 | 7 | 4 | 13 | 1 | 5 | 6 | 15 | 0.2 | 0.7 | 2 |
CD4/CD8 | 36/5 | 33/3 | 40/3 | 35/3 | 36/3 | 50/2 | 39/3 | 37/5 | 43/8 | 35/5 | 55/1 | 37/3 |
2B6+GK1.5− | 34 | 39 | 38 | 40 | 38 | 41 | 36 | 39 | 41 | 33 | 42 | 37 |
2B6+GK1.5+ | 5 | 3 | 4 | 3 | 5 | 2 | 5 | 2 | 3 | 4 | 6 | 2 |
Data presented from a single experiment of two repeats with pooled cells (105/sample) from 9 to 10 mice.
Based on lymphoid cell-like limits of cells collected from collagenase-digested vaginas. The numbers 1, 2, 3, and 5 for each treatment refer to weeks postinfection.