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. 2022 Jul 6;29(11):1751–1760. doi: 10.1038/s41417-022-00491-0

Table 1.

Metabolic tests and their associated inhibitors.

Dependency test Treatment 1 Treatment 2
Glutamine dependency BPTES Etomoxir + UK5099
Fatty acid dependency Etomoxir BPTES + UK5099
Glucose dependency UK5099 BPTES + Etomoxir

Calculation of dependency

Dependency%=baselineOCRtargetinhibitorOCRbaselineOCRallinhibitorsOCR×100