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. 2022 Jun 27;29(11):1731–1741. doi: 10.1038/s41417-022-00492-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A–D qRT–PCR and western blot analyses of the inhibition and overexpression efficiency of S100A9 in PCa cells. E, F Transwell assays showed that S100A9 suppressed the migration and invasion of PCa cells. G, H Wound-healing assays showed that S100A9 weakened the migration of PCa cells. I, J Transwell and wound-healing assays showed that the migration and invasion abilities enhanced by knocking down circ_0006156 were partially inhibited by overexpressing S100A9.