TABLE 3.
Influence of disease activity at time of index VTE at risk of recurrent VTE
SLEDAI‐2K | Events N/total | Follow‐up (years) | Incidence rate recurrence per 100 PY (95% CI) | Unadjusted HR (95% CI) | Adjusted a HR (95% CI) |
---|---|---|---|---|---|
Continuous | — | 0.9 (0.8–1.0) | 0.9 (0.8–1.1) | ||
≤4 | 5/12 | 58 | 8.6 (2.8–20.1) | Ref | |
>4 | 9/46 | 387 | 2.3 (1.1–4.4) | 0.3 (0.1–1.0) | 0.4 (0.1–1.8) |
Abbreviations: CI, confidence interval; HR, hazard ratio; PY, person‐years; SLE, systemic lupus erythematosus; SLEDAI‐2K, Systemic Lupus Erythematosus Disease Activity Index 2000.
Adjusted for presence of provoking factor and secondary APS at index VTE. SLEDAI‐2K score >4 is associated with active SLE (i.e., a flare).