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. 2022 Nov 14;6(8):e12839. doi: 10.1002/rth2.12839

TABLE 3.

Influence of disease activity at time of index VTE at risk of recurrent VTE

SLEDAI‐2K Events N/total Follow‐up (years) Incidence rate recurrence per 100 PY (95% CI) Unadjusted HR (95% CI) Adjusted a HR (95% CI)
Continuous 0.9 (0.8–1.0) 0.9 (0.8–1.1)
≤4 5/12 58 8.6 (2.8–20.1) Ref
>4 9/46 387 2.3 (1.1–4.4) 0.3 (0.1–1.0) 0.4 (0.1–1.8)

Abbreviations: CI, confidence interval; HR, hazard ratio; PY, person‐years; SLE, systemic lupus erythematosus; SLEDAI‐2K, Systemic Lupus Erythematosus Disease Activity Index 2000.

a

Adjusted for presence of provoking factor and secondary APS at index VTE. SLEDAI‐2K score >4 is associated with active SLE (i.e., a flare).