Table 1.
Comparison of laboratory indexes between intervention group and control group before and after treatment
| Index | Control group (n = 30) |
Mild-moderate group (n = 17) |
Severe group (n = 13) |
F(X2) | p | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Before | After | p | Before | After | p | Before | After | p | |||
| Age (years) | 54.8 ± 9.0 | - | - | 52.8 ± 10.3 | - | - | 51.1 ± 14.1 | - | - | - | - |
| Sex (male%) | 19(63%) | - | - | 6(35%) | - | - | 10(77%) | - | - | - | - |
| BMI (kg/m2) | 30.9 ± 4.5 | 30.2 ± 4.4 | 0.06 | 30.2 ± 3.3 | 30.2 ± 3.34 | 0.57 | 30.3 ± 4.2 | 30.2 ± 4.3 | 0.23 | 1.78 | 0.18 |
| WHR | 0.99 ± 0.07 | 0.97 ± 0.32 | 0.34 | 0.99 ± 0.06 | 1.00 ± 0.21 | 0.35 | 0.98 ± 0.09 | 0.97 ± 0.01 | 0.46 | 0.31 | 0.78 |
| Duration (years) | 6.7 ± 6.8 | - | 8.6 ± 6.5 | - | 4.0 ± 5.1 | - | - | - | |||
| AHI | 34.5 ± 20.4 | - | 16.0 ± 7.3 | 3.5 ± 2.2 | < 0.05 | 44.4 ± 14.2 | 4.5 ± 2.6 | < 0.05 | 1.25 | 0.27 | |
| SBP (mmHg) | 136.6 ± 7.6 | 130.3 ± 8.2 | 0.31 | 129.2 ± 3.9 | 130.3 ± 4.1 | 0.23 | 129.7 ± 3.5 | 127.3 ± 7.3 | 0.56 | 1.02 | 0.42 |
| DBP (mmHg) | 82.7 ± 13.9 | 83.0 ± 20.3 | 0.67 | 89.7 ± 7.4 | 86.4 ± 11.0 | 0.24 | 87.3 ± 6.5 | 80.4 ± 8.6 | 0.43 | 2.09 | 0.29 |
| FBG (mmol/L) | 9.14 ± 2.87 | 9.26 ± 2.54 | 0.55 | 9.25 ± 3.07 | 5.90 ± 0.86 | < 0.05 | 9.55 ± 3.26 | 5.85 ± 0.58 | < 0.05 | 23.98 | < 0.05 |
| PBG (mmol/L) | 13.20 ± 3.83 | 12.22 ± 2.32 | 0.18 | 13.81 ± 3.68 | 8.21 ± 1.26 | < 0.05 | 13.28 ± 4.29 | 7.72 ± 1.03 | < 0.05 | 39.29 | < 0.05 |
| HbA1c (%) | 8.65 ± 1.66 | 8.28 ± 1.39 | 0.09 | 8.81 ± 2.55 | 6.89 ± 0.89 | < 0.05 | 9.00 ± 1.92 | 7.02 ± 1.01 | < 0.05 | 9.41 | < 0.05 |
| TC (mmol/L) | 4.77 ± 1.32 | 4.83 ± 0.99 | 0.79 | 5.24 ± 0.85 | 4.69 ± 0.97 | 0.10 | 4.78 ± 0.85 | 4.71 ± 1.22 | 0.86 | 0.11 | 0.89 |
| TG (mmol/L) | 2.39 ± 1.68 | 2.34 ± 1.16 | 0.91 | 2.78 ± 1.64 | 2.04 ± 1.30 | 0.21 | 2.34 ± 1.53 | 2.04 ± 1.59 | 0.67 | 0.40 | 0.67 |
| LDL-C (mmol/L) | 2.51 ± 1.39 | 2.58 ± 0.64 | 0.81 | 3.24 ± 1.16 | 2.72 ± 0.68 | 0.15 | 2.93 ± 0.72 | 2.54 ± 0.79 | 0.14 | 0.32 | 0.73 |
| HDL-C (mmol/L) | 1.08 ± 0.45 | 0.99 ± 0.21 | 0.32 | 1.10 ± 0.65 | 1.13 ± 0.26 | 0.90 | 0.96 ± 0.18 | 1.07 ± 0.24 | 0.17 | 0.98 | 0.38 |
| UA (umol/L) | 399.9 ± 87.3 | 350.6 ± 81.3 | 0.06 | 361.0 ± 131.5 | 315.6 ± 81.6 | 0.34 | 334.4 ± 84.0 | 320.2 ± 85.1 | 0.65 | 1.29 | 0.28 |
| sCr (mmol/L) | 80.6 ± 30.5 | 69.4 ± 17.2 | 0.10 | 66.2 ± 16.2 | 68.9 ± 16.3 | 0.62 | 69.9 ± 18.0 | 72.7 ± 24.5 | 0.77 | 0.39 | 0.68 |
| UACR | 31.4 ± 32.1 | 8.9 ± 5.7 | < 0.05 | 32.3 ± 67.9 | 9.9 ± 5.8 | 0.24 | 34.0 ± 69.0 | 24.7 ± 55.4 | 0.06 | 0.56 | 0.58 |
| HOMA-IR | 4.28 ± 3.70 | 3.28 ± 2.53 | 0.22 | 3.89 ± 2.07 | 2.21 ± 1.27 | < 0.05 | 2.98 ± 1.78 | 2.82 ± 1.94 | 0.78 | 1.37 | 0.26 |
BMI body mass index; WHR waist-to-hip ratio; SBP systolic blood pressure; DBP diastolic blood pressure; FBG fasting blood glucose; HbA1c glycosylated hemoglobin; sCr serum creatinine; UA uric acid; TC total cholesterol; TG triglycerides; LDL-C low-density lipoprotein cholesterol; HDL-C high-density lipoprotein cholesterol; PBG postprandial blood glucose; UACR urinary microalbumin/creatinine ratio; HOMA-IR homeostasis model assessment index of insulin resistance