Table 1.
Groups | NEC groups (N1-N4) | Control group (C1-C4) | ||||||
---|---|---|---|---|---|---|---|---|
Infants | N1 | N2 | N3 | N4 | C1 | C2 | C3 | C4 |
Gestational Age (w+d) | 32+2 | 28+3 | 25+6 | 27+2 | 38 | 39 | 29+1 | 26+1 |
Birth weight (g) | 1380 | 1260 | 990 | 1200 | 3100 | 3990 | 980 | 740 |
Age of onset of NEC (d) | 29 | 28 | 50 | 37 | – | – | 10 | 51 |
Delivery mode | Caesarean section | Caesarean section | Caesarean section | Vaginal delivery | Vaginal delivery | Vaginal delivery | Caesarean section | Caesarean section |
Hs-CRP* in acute phase of NEC (mg/L) | 69.48 | 10.83 | 67.85 | 88.56 | 1.37 | 1.13 | 59.88 | 94.31 |
Clinical diagnosis | Acute stage of NEC | Acute stage of NEC | Acute stage of NEC | Acute stage of NEC | Congenital anal atresia | Congenital jejunal atresia | Recovery stage of NEC | Recovery stage of NEC |
Surgical pathologic staging | NEC III | NEC IIb (multifocal lesions) | NEC IIIa | NEC IIIa | – | – | – | – |
Complication | RDS*, PDA*, Neonatal cholestasis, Sepsis, Short bowel syndrome | RDS*, BPD*, PDA*, Sepsis, Neonatal cholestasis, Intraventricular hemorrhage | RDS*, BPD*, PDA*, ROP*, Sepsis, Neonatal cholestasis | RDS*, PDA*, infantile hepatitis syndrome | – | – | RDS*, Sepsis | RDS*, BPD*, PDA*, Sepsis, ROP*, infantile hepatitis syndrome |
*hs-CRP: hypersensitive C-reactive protein, RDS: Respiratory distress syndrome, BPD: Bronchopulmonary Dysplasia, ROP: Retinopathy of Prematurity, PDA: Patent ductus arteriosus. The normal range of hs-CRP is less than 8 mg/L. N1-4 stand for patients in NEC group, C1-4 stand for patients in control group.