Table 1.
Hepatotoxic and Cardiotoxic compounds.
| Hepatotoxic compounds(abbreviation) | Drug class | Cardiotoxic compounds (abbreviation) | Drug class |
|---|---|---|---|
| Fluorouracil (5FU) | antimetabolites | Fluorouracil (5FU) | Antimetabolites |
| Acetaminophen (APAP) | analgesics and antipyretics | Doxorubicin (DOX) | Anthracyclines |
| Azathioprine (AZA) | immunosuppressants | Epirubicin (EPI) | Anthracyclines |
| Cyclosporin A (CYC) | immunosuppressants | Idarubicin (IDA) | Anthracyclines |
| Diclofenac (DIC) | NSAIDs | Daunorubicin (DAU) | Anthracyclines |
| Isoniazid (ISO) | antituberculosis agents | Amiodarone (AMI) | Antiarrhythmics |
| Methotrexate (MTX) | antimetabolites | Celecoxib (CEL) | NSAIDs, COX-2 inhibitors |
| Phenytoin (PHE) | anticonvulsants | Docetaxel (DOC) | Taxanes |
| Rifampicin (RIF) | antimycobacterials | Mitoxantrone (MIT/MXT) | Anthracenediones |
| Valproic acid (VPA) | anticonvulsants | Paclitaxel (PAC/PTX) | antimicrotubule agents |
Drug classes were obtained from MedlinePlus. U.S. National Library of Medicine44.