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Period of PBmal1::Fluc oscillation calculated for each DOX concentration.
| DOX concentration (µg/mL) | 10 | 1 | 0.1 | 0.05 | 0.02 | 0.01 |
|---|---|---|---|---|---|---|
| Period (τ) (h) | 25.7 | 25.0 | 25.3 | 25.0 | 24.7 | N.D |
Data from 0 to 144 h shown in Fig. 1B were detrended using 6th-order polynomials and subjected to a chi-square periodogram analysis using Lumicycle analysis software (ActiMetrics; Wilmette, IL, USA).
