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. 2022 Nov 14;12:19525. doi: 10.1038/s41598-022-23817-2

Table 2.

Donor baseline characteristics for the study cohorts.

N Ext. validation 2017–2018
N = 4750
Test 2014–2016
N = 6120
Train/val. 1987–2013
N = 31,315
Test statistic
Donor age (yrs)*,† 42,185

24 31 40

33 ± 11

23 31 41

32 ± 11

21 30 42

32 ± 12

F2 42182 = 18, P < 0.0012
Donor female gender* 42,185 30%14434750 30%18286120 29%921431,315 χ22 = 2.1, P = 0.361
Donor height (cm)* 42,144

168.0 175.0 180.3

174.0 ± 9.6

167.6 175.0 180.3

173.8 ± 9.6

167.6 175.3 182.9

174.6 ± 9.5

F2 42141 = 19, P < 0.0012
Donor weight (kg)* 42,179

70 81 95

84 ± 19

70 80 93

83 ± 20

68 79 90

81 ± 18

F2 42176 = 69, P < 0.0012
Donor ABO blood type* 42,184 χ26 = 7.7, P = 0.261
A 36.7%17454750 35.3%21636120 36.4%11,41331,314
AB 2.1%994750 2.5%1546120 2.3%70631,314
B 10.9%5204750 11.3%6906120 10.5%329531,314
O 50.2%23864750 50.9%31136120 50.8%15,90031,314
Donor cause of death* 42,149 χ28 = 2669, P < 0.0011
Anoxia 38.2%18134748 29.8%18236118 12.3%385031,283
Cerebrovascular/stroke 14.8%7034748 19.1%11666118 25.6%800031,283
CNS tumor 0.5%234748 0.3%216118 1.0%31331,283
Head trauma 44.6%21194748 48.6%29716118 59.3%18,54431,283
Other 1.9%904748 2.2%1376118 1.8%57631,283
Ischemic time (min)*,† 40,394

138 184 223

183 ± 64

143 186 227

187 ± 62

146 188 229

190 ± 63

F2 40391 = 23, P < 0.0012
Recipient-donor height ratio* 42,037

0.963 1.000 1.036

1.000 ± 0.056

0.967 1.000 1.040

1.002 ± 0.057

0.958 1.000 1.036

0.998 ± 0.061

F2 42034 = 16, P < 0.0012
Recipient-donor weight ratio* 42,086

0.87 1.03 1.18

1.03 ± 0.23

0.88 1.02 1.17

1.03 ± 0.22

0.88 1.02 1.16

1.02 ± 0.21

F2 42083 = 2.6, P = 0.0712

a b c represents the lower quartile a, the median b, and the upper quartile c for continuous variables. x ± s represents X ± 1 SD. N is the number of non-missing values. Variables included in * IHTSA, # IMPACT, and PRN model. CNS, Central nervous system tumours. Tests used: 1Pearson test; 2Kruskal–Wallis test.