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. 2022 Nov 1;13:1009316. doi: 10.3389/fgene.2022.1009316

TABLE 1.

Selected scRNAseq data integration methods.

Tool Input Strategy Reference
ComBat-seq raw counts linear model Zhang et al. (2020)
limma logcounts linear model Leek et al. (2012)
MNN logcounts mutual nearest neighbors (gene expression space) Haghverdi et al. (2018)
scMerge logcounts stably expressed genes + RUV model Lin et al. (2019)
Seurat logcounts canonical correlation analysis + mutual nearest neighbors Stuart et al. (2019)
Scanorama raw counts mutual nearest neighbors (reduced space) + panoraming stiching  Hie et al. (2019)