TABLE 1.
Tool | Input | Strategy | Reference |
---|---|---|---|
ComBat-seq | raw counts | linear model | Zhang et al. (2020) |
limma | logcounts | linear model | Leek et al. (2012) |
MNN | logcounts | mutual nearest neighbors (gene expression space) | Haghverdi et al. (2018) |
scMerge | logcounts | stably expressed genes + RUV model | Lin et al. (2019) |
Seurat | logcounts | canonical correlation analysis + mutual nearest neighbors | Stuart et al. (2019) |
Scanorama | raw counts | mutual nearest neighbors (reduced space) + panoraming stiching | Hie et al. (2019) |