Table 2.
Factors associated with 180-day mortality after severe traumatic brain injury.
| The dead | The alive | P-value | |
|---|---|---|---|
| Gender (male/female) | 16/10 | 44/35 | 0.602 |
| Age (y) | 47.6 ± 16.2 | 40.5 ± 13.1 | 0.026 |
| Current cigarette smoking | 11 (42.3%) | 21 (26.6%) | 0.131 |
| Alcohol abuse | 11 (42.3%) | 22 (27.9%) | 0.168 |
| Hypertension | 7 (26.9%) | 10 (12.7%) | 0.123 |
| Diabetes mellitus | 5 (19.2%) | 7 (8.9%) | 0.166 |
| Hyperlipidemia | 5 (19.2%) | 12 (15.2%) | 0.759 |
| Hospital admission time (h) | 4.5 (2.9–5.5) | 5.1 (3.9–6.5) | 0.117 |
| Blood-sampling time (h) | 5.2 (3.6–7.5) | 6.8 (4.9–8.4) | 0.100 |
| Traumatic causes | 0.391 | ||
| Automobile/motorcycle | 15 | 37 | |
| Fall/jump | 8 | 36 | |
| Others | 3 | 6 | |
| GCS scores | 4 (3–4) | 5 (5–7) | < 0.001 |
| Rotterdam CT scores | 6 (5–6) | 4 (4–5) | < 0.001 |
| Systolic arterial pressure (mmHg) | 126.2 ± 29.2 | 125.6 ± 29.8 | 0.925 |
| Diastolic arterial pressure (mmHg) | 76.0 ± 17.4 | 73.6 ± 17.1 | 0.532 |
| Blood glucose levels (mmol/l) | 10.4 (8.6–12.6) | 8.4 (6.8–10.9) | 0.003 |
| Blood leucocyte count ( × 109/l) | 8.5 (6.2–10.8) | 7.3 (5.8–9.6) | 0.478 |
| Serum Nrf2 levels (ng/ml) | 12.9 (11.0–15.2) | 10.3 (8.3–12.4) | < 0.001 |
Data were shown as mean ± standard deviation, median (25–75th percentiles), or count (percentage) where appropriate. Statistical methods for intergroup comparison included the t-test, Mann–Whitney U test, Pearson Chi-square test, or Fisher's exact test as appropriate. CT, computerized tomography; GCS, Glasgow Coma Scale; Nrf2, nuclear factor erythroid 2-related factor 2.