Table 3.
Factors associated with 180-day overall survival after severe traumatic brain injury.
| Hazard ratio | 95% CI | P-value | |
|---|---|---|---|
| Gender (male/female) | 1.218 | 0.553–2.685 | 0.624 |
| Age (y) | 1.031 | 1.003–1.059 | 0.028 |
| Current cigarette smoking | 1.688 | 0.775–3.675 | 0.187 |
| Alcohol abuse | 1.678 | 0.770–3.653 | 0.193 |
| Hypertension | 2.089 | 0.878–4.972 | 0.096 |
| Diabetes mellitus | 2.116 | 0.798–5.612 | 0.132 |
| Hyperlipidemia | 1.267 | 0.478–3.359 | 0.635 |
| Hospital admission time (h) | 0.904 | 0.772–1.057 | 0.207 |
| Blood-sampling time (h) | 0.899 | 0.783–1.034 | 0.136 |
| Traumatic causes | |||
| Automobile/motorcycle | Reference | ||
| Fall/jump | 0.798 | 0.231–2.757 | 0.724 |
| Others | 0.506 | 0.134–1.907 | 0.314 |
| GCS scores | 0.374 | 0.249–0.561 | < 0.001 |
| Rotterdam CT scores | 3.783 | 2.315–6.182 | < 0.001 |
| Systolic arterial pressure (mmHg) | 1.001 | 0.988–1.014 | 0.921 |
| Diastolic arterial pressure (mmHg) | 1.008 | 0.985–1.032 | 0.484 |
| Blood glucose levels (mmol/l) | 1.120 | 1.025–1.225 | 0.013 |
| Blood leucocyte count ( × 109/l) | 1.059 | 0.929–1.206 | 0.394 |
| Serum Nrf2 levels (ng/ml) | 1.324 | 1.179–1.488 | < 0.001 |
Associations were reported as hazard ratios using univariate Cox's proportional hazard regression analysis. CT, computerized tomography; GCS, Glasgow Coma Scale; Nrf2, nuclear factor erythroid 2-related factor 2; 95% CI, 95% confidence interval.