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. 2022 Nov 15;12:19547. doi: 10.1038/s41598-022-23793-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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A scatterplot shows center log-ratio-transformed relative abundances of the phylum Tenericutes plotted against Center for Epidemiological Studies Depression Scale (CES-D) total score. Each dot represents the relative abundance of the phylum Tenericutes in one sample and the corresponding participant’s total CES-D score. A Spearman correlation test revealed a negative correlation between Tenericutes relative abundance and CES-D score (r = − 0.5, p = 0.002), indicating that a higher relative abundance of Tenericutes was associated with lower severity of depressive symptoms.