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. 2022 Nov 15;12:19547. doi: 10.1038/s41598-022-23793-7

Table 5.

Hierarchical multiple linear regression analysis with the predicted variable as cognitive impairment as measured by FACT-Cog total score.

Variable Block 1 Block 2 Block 3
B SE B β B SE B β B SE B β
Group 25.9 6.9 0.6*** 20.3 7.7 0.5* 19.4 9.0 0.4*
Age − 0.2 0.2 − 0.1 − 0.2 0.2 − 0.2 − 0.3 0.3 − 0.2
CES-D − 0.7 0.4 − 0.2 − 0.7 0.5 − 0.2
Verrucomicrobia 0.2 0.8 0.03
R2 0.4 0.5 0.5
F for changes in R2 10.1*** 7.8*** 5.7**

Verrucomicrobia relative abundance was analyzed utilizing a center log-ratio transformation. F for changes in R2 F test for R-squared changes in model, *p < 0.05, **p < 0.01, ***p < 0.001.

β, beta power; B, unstandardized beta coefficient; CES-D Center for Epidemiologic Studies Depression Scale; R2, R-squared; SE B, standardized beta coefficient.