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. 2022 Nov 1;10:1048148. doi: 10.3389/fcell.2022.1048148

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Copyright © 2022 Zhang, Zhang, Chan, Ma, Lu, Yu, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Different modification approach resulted in different aptamer proportion in the drug. Note: MW is short for the molecular weight; PEG-MAL is short for the polyethylene glycol maleimide.