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. 2022 Sep 15;81(12):1661–1668. doi: 10.1136/ard-2022-222630

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Patient disposition. *One patient was randomised to OKZ 64 mg q4w but actually received OKZ 64 mg q2w. Patients who discontinued treatment early and entered safety follow-up period were considered completers for the whole study if they performed all three follow-up visits. Therefore, the number of those who completed study can be higher than the number of treatment completers. AE, adverse event; IC, informed consent; ITT, intention-to-treat; MTX, methotrexate; N, number patient in the arm; N (%), number (%) patients; %, the percentage of subjects is calculated relative to the total number of subjects in the population; OKZ, olokizumab; OLE, open-label extension; PBO, placebo; q2w, every 2 weeks; q4w, every 4 weeks.